Article

On Casein Kinase-2 (CK2) deregulation in NSCLC: an enzyme subunit-centered approach

2023-08-04

Abstract excerpt

CK2 is considered a constitutively active protein kinase promoting/supporting several neoplastic properties and inducing a so-called non-oncogene addiction in tumor cells. Compared to the extensive body of pre-clinical research, the translational and clinical information on CK2 is still limited. The holoenzyme, composed by a tetrameric array of two catalytic (CSNK2A1 and/or CSNK2A1) and two regulatory (CSNK2B) sub...

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Literature Corpus work: e2ab6e6d-526f-5b37-a2ed-bf0d43eb50dc
DOI: 10.1101/2023.08.04.551954

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