Article

HSF1-dependent augmentation of aerobic glycolysis by NEK2 fuels lung adenocarcinoma progression

2026-06-17

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Lung adenocarcinoma (LUAD), accounting for 50% of non-small cell lung cancer cases, exhibits dismal survival rates due to therapy resistance and metabolic adaptation. While NIMA related kinase 2 (NEK2), a mitotic kinase, is implicated in tumor progression, its mechanistic role in LUAD-associated glycolysis remains elusive. <bold>Materials and Methods:</bold...

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Literature Corpus work: 6a76a3c2-04d9-5fb6-8294-351a20d78ed3
DOI: 10.21203/rs.3.rs-7715304/v1

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