Article

Crosstalk of Wnt Signaling Activation and H3K27me3 Epigenetic Modulation in Colorectal Cancer: A Single-Center Population Study from Romania

2026-02-11

Abstract excerpt

Colorectal cancer is a heterogeneous malignancy characterized by alterations in onco-genic signaling pathways and epigenetic mechanisms involved in gene regulation. Ab-errant activation of the Wnt/β-catenin pathway represents a central molecular event in colorectal tumorigenesis, while histone-associated epigenetic modifications may contribute to tumor progression and variability. This study aimed to investigate t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e29c3045-0a18-59af-9dab-50eb146924b9
DOI: 10.20944/preprints202602.0858.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Crosstalk of Wnt Signaling Activation and H3K27me3 Epigenetic Modulation in Colorectal Cancer: A Single-Center Population Study from RomaniaDOI 10.20944/preprints202602.0858.v1Read

Advances of Wnt Signalling Pathway in Colorectal CancerSemantic proximity Read

Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosaSemantic proximity Read

Therapeutic targeting of the oncogenic Wnt signaling pathway for treating colorectal cancer and other colonic disorders.Semantic proximity Read

Targeting the Most Upstream Site of Wnt Signaling Pathway Provides a Strategic Advantage for Therapy in Colorectal CancerSemantic proximity Read

Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer PatientsSemantic proximity Read

The genetic factors associated with Wnt signaling pathway in colorectal cancer.Semantic proximity Read

Regulation of Wnt receptor activity: Implications for therapeutic development in colon cancer.Semantic proximity Read

The role of the Wnt signalling pathway in colorectal tumorigenesis.Semantic proximity Read

ZEB1 Hypermethylation Is Associated with Better Prognosis in Patients with Colon CancerSemantic proximity Read

Crosstalk Between DNA Methylation and Gene Mutations in Colorectal CancerSemantic proximity Read

Wnt–β-catenin as an epigenetic switcher in colonic Treg cellsSemantic proximity Read

RUNX3 Inactivation in Colorectal Polyps Arising Through Different Pathways of Colonic CarcinogenesisSemantic proximity Read