Article

Pneumococcal competence, a populational health sensor driving multilevel heterogeneity in response to antibiotics

2023-11-17

Abstract excerpt

Competence for natural transformation is a central driver of genetic diversity in bacteria. In the human pathogen Streptococcus pneumoniae , competence exhibits a populational character mediated by the stress-induced ComABCDE quorum-sensing (QS) system. Here, we explore how this cell-to-cell communication mechanism proceeds and the functional properties acquired by competent cells grown under lethal stress. We sh...

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Literature Corpus work: e25cced1-630f-53b2-bc14-b5d625fc7423
DOI: 10.1101/2023.11.17.567514

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