Article

Oncogenic RAS-driven α2 integrin induction under nutrient stress promotes cancer cell motility

2026-04-06

Abstract excerpt

Cancer metabolism rewiring is one of the hallmarks of cancer, enabling cancer cell survival in a nutrient deprived microenvironment. Key to this is nutrient scavenging where cancer cells rely on extracellular proteins, including extracellular matrix (ECM) components, to sustain their proliferation. ECM uptake is mediated by α2β1 integrin, however it is not clear how this process is controlled by nutrient availabil...

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Literature Corpus work: e25a08db-c09c-579b-841d-bc6cd83273c9
DOI: 10.64898/2026.04.02.716145

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