Article

Two Families of GTPases Dominate the Complex Cellular Response to IFN-γ

1998-12-01

Abstract excerpt

Abstract IFN-γ induces a number of cellular programs functional in innate and adaptive resistance to infectious pathogens. It has recently become clear that the complete cellular response to IFN-γ is extraordinarily complex, with >500 genes (i.e., ∼0.5% of the genome) activated. We made suppression-subtractive hybridization differential libraries from IFN-γ-stimulated primary mouse embryonic fibroblasts and from a...

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Literature Corpus work: e24602d8-10b5-5fea-a717-3ece26e6b357
DOI: 10.4049/jimmunol.161.12.6715

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