Article

Combined Signaling of NF-kappaB and IL-17 Contributes to Mesenchymal Stem Cells-Mediated Protection for Paraquat-induced Acute Lung Injury

2020-03-03

Abstract excerpt

<h4>Background: </h4> Paraquat (PQ) is a widely used herbicide and it can cause pulmonary toxicity and even acute lung injury. Treatment for PQ poisoning in a timely manner is still a challenge for clinicians. Mesenchymal stem cell (MSC) transplantation has hold much potentials for the treatment of several diseases including PQ poisoning. The aim of this study is to examine the mechanisms that MSCs mediate for the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e21a245b-01cb-5ecf-9bb9-db8c79a8b265
DOI: 10.21203/rs.3.rs-15880/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Combined Signaling of NF-kappaB and IL-17 Contributes to Mesenchymal Stem Cells-Mediated Protection for Paraquat-induced Acute Lung InjuryDOI 10.21203/rs.3.rs-15880/v1Read

Identification of Hub Genes and Key Pathways of Paraquat Induced Human Embryonic Pulmonary Fibrosis by Bioinformatics Analysis and Vitro ExperimentsSemantic proximity Read

Identification of differentially expressed genes and pathways in diquat and paraquat poisoning using bioinformatics analysisSemantic proximity Read

Qilongtian Ameliorate Bleomycin-induced Pulmonary Fibrosis in Mice via Inhibiting IL-17 signal pathwaySemantic proximity Read

Exploring the mechanism of astaxanthin against lipopolysaccharide-induced acute lung injury by network pharmacology and experimental validationSemantic proximity Read

Paraquat Modulates Immunological Function in Bone Marrow-Derived MacrophagesSemantic proximity Read

Integrated long non‐coding RNA analyses identify novel regulators of epithelial‐mesenchymal transition in the mouse model of pulmonary fibrosisSemantic proximity Read

LncRNA HOTAIR Increases Inflammatory Responses by Activating NF-κB Pathway in LPS-Induced Acute Lung InjurySemantic proximity Read

Activated microglia contribute to paraquat neurotoxicity through neuroinflammation and regulation of phenotypic polarization of astrocytes.Semantic proximity Read

HPMSCs Inhibit the Expression of PD-1 in CD4+IL-10+ T Cells and Mitigate liver Damage in a GVHD Mouse Model by Regulating the Cross-talk Between Nrf2 and NF-κB Signaling PathwaySemantic proximity Read

Characterization of Paraquat-Induced miRNA Profiling Response in hNPCs Undergoing ProliferationSemantic proximity Read

Umbilical cord mesenchymal stem cell alleviates asthma via Nrf2/HO-1/NF-κB signaling pathwaySemantic proximity Read

Luteolin attenuate paraquat-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathwaySemantic proximity Read