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A proteogenomic approach to identifying a gene signature associated with <i>HOXB13</i> G84E carrier status in prostate cancer tumours

2025-07-10

Abstract excerpt

<h4>ABSTRACT</h4> The rare HOXB13 G84E variant is one of few established high-risk prostate cancer variants, yet the underlying molecular mechanisms by which it drives tumour development remain poorly understood. Prostate tumours from six G84E variant carriers and 18 non-carriers (wildtype) were examined using the Human AmpliSeq Transcriptome Gene Expression Panel and mass spectrometry. We identified a 799-gene e...

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Literature Corpus work
e1fcffcb-a9a1-5a29-9b47-e0ca7b222ead
DOI
10.1101/2025.07.08.25331050
Open publication

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A proteogenomic approach to identifying a gene signature associated with <i>HOXB13</i> G84E carrier status in prostate cancer tumoursDOI 10.1101/2025.07.08.25331050
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