Article

Personalized circulating tumor DNA dynamics predict survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer

2025-01-28

Abstract excerpt

<h4>Background</h4> Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) is an aggressive cancer with a median overall survival of only 12 months. Existing biomarkers have limited ability to predict treatment response or survival, exposing many patients to the potential toxicity of treatment without certain clinical benefit. Circulating tumor DNA (ctDNA) has emerged as a non-invasive, real-time b...

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Literature Corpus work: e1f4b7a0-a522-5c56-be53-2e34dc222097
DOI: 10.1101/2025.01.27.25321198

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