Article
The Prognostic and Therapeutic Value of the Mutational Profile of Blood and Tumor Tissue in Head and Neck Squamous Cell Carcinoma.
The oncologist - 1 Feb 2021
Wilson Harper L, D'Agostino Ralph B, Meegalla Nuwan, Petro Robin, Commander Sara, Topaloglu Umit, Zhang Wei, Porosnicu Mercedes
Abstract excerpt
BACKGROUND: The purpose of this study was to explore the genomic landscape of head and neck squamous cell carcinoma (HNSCC) in circulation (circulating tumor DNA [ctDNA]) and tumor (tumor tissue DNA [tDNA]) and understand the implications of ctDNA sequencing for prognosis and precision oncology treatments. MATERIALS AND METHODS: This is a retrospective review of 75 patients with HNSCC for both tDNA and ctDNA....
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