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Article

The Cap-Snatching Mechanism of Bunyaviruses

13 Jan 2020

Abstract excerpt

In common with all segmented negative-sense RNA viruses, bunyavirus transcripts contain heterologous sequences at their 5' termini originating from capped host cell RNAs. These heterologous sequences are acquired by a so-called cap-snatching mechanism. Whereas for nuclear replicating influenza virus the source of capped primers as well as the cap-binding and endonuclease activities of the viral polymerase needed...

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PMID: 31948728
DOI: 10.1016/j.tim.2019.12.006

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