Article
Circular RNAs from the MAPT and TARDP Genes: Novel Players in Neurodegeneration?
2025-05-27
Abstract excerpt
The microtubule associated protein tau (MAPT) and TAR DNA binding protein (TARDBP) genes play crucial roles in neurodegeneration. The tau protein encoded by MAPT is the main component of tau tangles, a pathologic hallmark of “tauopathies” such as Alzheimer’s disease (AD). Cytosolic accumulations of TDP-43, encoded by TARDBP are characteristic for LATE (Limbic-predominant age-related TDP-43 encephalopathy) and othe...
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Identifiers and source
- Literature Corpus work
- 9361f36f-7fa3-5688-8f78-8d90f77dd5b9
- DOI
- 10.20944/preprints202505.2117.v1
