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Article

Regulatory mechanism of circular RNAs in neurodegenerative diseases

21 Oct 2023

Abstract excerpt

BACKGROUND: Neurodegenerative disease is a collective term for a category of diseases that are caused by neuronal dysfunction, such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). Circular RNAs (circRNAs) are a class of non-coding RNAs without the 3' cap and 5' poly(A) and are linked by covalent bonds. CircRNAs are highly expressed in brain neurons and can regulate...

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PMID: 37864389
DOI: 10.1111/cns.14499

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