Article

Discoidins are cytosolic lectins that shape intracellular host defence by sensing virulence-associated mycobacterial glycolipids and glycopeptidolipids

2026-06-19

Abstract excerpt

Mycobacteria are surrounded by a dynamic, glycolipid-rich envelope that controls both virulence and immune recognition, yet how cytosolic lectins detect and interpret the organization of surface glycans during intracellular infection remains unclear. Here, we show that Dictyostelium discoideum discoidins act as cytosolic sensors of mycobacterial envelope organization. During Mycobacterium marinum infection, Disc...

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Literature Corpus work: e1c5e9e3-bfd2-54fe-a972-2b5722584496
DOI: 10.64898/2026.06.18.733164

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Discoidins are cytosolic lectins that shape intracellular host defence by sensing virulence-associated mycobacterial glycolipids and glycopeptidolipidsDOI 10.64898/2026.06.18.733164Read

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