Article
Immunochemical, genetic and morphological comparison of fucosylation mutants of Dictyostelium discoideum.
Microbiology (Reading, England) - 1 Apr 1995
Champion A, Griffiths K, Gooley A A, Gonzalez B Y, Gritzali M, West C M, Williams K L
Abstract excerpt
Mutations in three loci in Dictyostelium discoideum which affect fucosylation are described. Mutations in two of these loci resulted in the simultaneous loss of two separate carbohydrate epitopes. The GA-X epitope, which was competed by L-fucose, was absent in strains carrying a modC354, modD352 or modE353 mutation. These strains exposed a new carbohydrate epitope, competed by N-acetylglucosamine, and the size of...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Fungal
- Antigens, Protozoan
- Dictyostelium
- Epitopes
- Fucose
- Genes, Fungal
- Genes, Protozoan
- Glycosylation
- Immunochemistry