Article

Investigating Primary Cilia during Peripheral Nervous System Formation

2021-02-01

Abstract excerpt

The primary cilium plays a pivotal role during embryonic development of vertebrates. It acts as a somatic signaling hub for specific pathways, such as sonic hedgehog signaling. In humans, mutations in genes that cause dysregulation of ciliogenesis or ciliary function lead to severe developmental disorders called ciliopathies. Beyond its obvious role in early morphogenesis, growing evidence points towards an essent...

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Literature Corpus work: e1aea00c-edba-5b33-b0c1-2d0c0b02e7e0
DOI: 10.20944/preprints202102.0031.v1

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