Article

Cell-autonomous regulation of astrocyte activation by the circadian clock protein BMAL1

2018-07-05

Abstract excerpt

<h4>Summary</h4> Circadian clock dysfunction is a common symptom of aging and neurodegenerative diseases, though its impact on brain health is poorly understood. Astrocyte activation occurs in response to diverse insults, and plays a critical role in brain health and disease. We report that the core clock protein BMAL1 regulates astrogliosis in a synergistic manner via a cell-autonomous mechanism, and via a lesse...

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Literature Corpus work: e1904b63-5fed-5120-8bdb-e7564f3cafdd
DOI: 10.1101/362814

Open publication

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