Article

Diastolic Dysfunction in Congenital Heart Disease: A Pressure-Volume Loop Analysis of Borderline Left Heart

2026-01-16

Abstract excerpt

<h4>Background</h4> Diastolic dysfunction is a major driver of morbidity in congenital heart disease (CHD), but its mechanisms are poorly understood. It remains unknown whether left ventricular (LV) diastolic dysfunction in borderline left heart patients is caused by a defect in active relaxation or in passive compliance. <h4>Objectives</h4> We sought to apply gold-standard pressure-volume (PV) loop analysis to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e18d957c-e708-5caf-a54b-7772dd598850
DOI: 10.64898/2026.01.13.26344073

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Diastolic Dysfunction in Congenital Heart Disease: A Pressure-Volume Loop Analysis of Borderline Left HeartDOI 10.64898/2026.01.13.26344073Read

Assessment of a Non-Invasive Approach for Pressure Volume Loop Prediction in MiceSemantic proximity Read

Enhanced diastolic dysfunction but preserved systolic function after acute pressure overload in the absence of smoothelin-like 1 proteinSemantic proximity Read

Biomechanics of diastolic dysfunction: a one-dimensional computational modeling approach.Semantic proximity Read

Low Ventricular Stiffness Is Associated With Suboptimal Outcomes in Patients With a Single Right Ventricle After the Fontan Operation: A Novel Phenotype.Semantic proximity Read

Non-Invasive Quantification of Pressure-Volume Loops in Patients with Fontan CirculationSemantic proximity Read

DIA-PINN. A physics-informed machine learning method to estimate global intrinsic diastolic chamber properties of the left ventricle from pressure-volume dataSemantic proximity Read

Preserved and reduced ejection fraction manifest as two mechanistically unique phenotypes of diastolic dysfunctionSemantic proximity Read

Presurgical Pulmonary Function Tests in the First Few Days of Life in Neonates with Congenital Heart Disease, A Pilot StudySemantic proximity Read

Stiffness of ascending aorta has a direct impact on left ventricular function: In silico modelSemantic proximity Read

Predictive modeling of secondary pulmonary hypertension in left ventricular diastolic dysfunctionSemantic proximity Read

A comprehensive characterization of myocardial and vascular phenotype in pediatric chronic kidney disease using cardiovascular magnetic resonance imaging.Semantic proximity Read

The Preterm Heart in Childhood: Left Ventricular Structure, Geometry, and Function Assessed by Echocardiography in 6-Year-Old Survivors of Periviable Births.Semantic proximity Read