Article

Preserved and reduced ejection fraction manifest as two mechanistically unique phenotypes of diastolic dysfunction

2025-08-19

Abstract excerpt

<h4>Background</h4> Diastolic dysfunction is present in both heart failure with preserved (pEF) and reduced (rEF) ejection fraction (EF). However, differences in treatment response suggest that these classifications represent two unique phenotypes of diastolic dysfunction. We hypothesized that pEF and rEF would exhibit different mechanics of diastolic dysfunction. <h4>Methods</h4> Patients undergoing echocardiog...

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Literature Corpus work: 8ddb4bee-6580-5686-9511-45e4d2609e74
DOI: 10.1101/2025.08.17.25332552

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