Article
Sex disparity in acute myeloid leukemia – evidence from a study of <i>FLT3</i>-ITD mutated patients
2020-09-07
Abstract excerpt
Little attention has been directed at untangling sex-related molecular and phenotypic differences in AML. While increased incidence and poor risk is generally associated with a male phenotype, FLT3 -ITD, NPM1 and DNMT3A mutations are overrepresented in female AML. Here, we have investigated the relationship between sex and FLT3 -ITD mutation status by comparing clinical data, mutational profiles, gene expression a...
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Identifiers and source
- Literature Corpus work
- e17e3880-b895-5880-b0d9-33daec4ae862
- DOI
- 10.1101/2020.09.04.20188219