Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis.

Molecular oncology - 1 Sept 2021

Hellesøy Monica, Engen Caroline, Grob Tim, Löwenberg Bob, Valk Peter J M, Gjertsen Bjørn T

Abstract excerpt

Incidence, molecular presentation and outcome of acute myeloid leukaemia (AML) are influenced by sex, but little attention has been directed at untangling sex-related molecular and phenotypic differences between female and male patients. While increased incidence and poor risk are generally associated with a male phenotype, the poor prognostic FLT3 internal tandem duplication (FLT3-ITD) mutation and co-mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Neoplasm
Share to fms-Like Tyrosine Kinase 3

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Duplication

Share to Gene Expression Profiling

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Prognosis

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 34101344
DOI: 10.1002/1878-0261.13035
PMCID: PMC8410575

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex disparity in acute myeloid leukaemia with FLT3 internal tandem duplication mutations: implications for prognosis.PMID 34101344Read ↗

Sex disparity in acute myeloid leukemia – evidence from a study of <i>FLT3</i>-ITD mutated patientsSemantic proximity Read ↗

Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG).Semantic proximity Read ↗

Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG)Semantic proximity Read ↗

Sex-Related Differences in Chronic Myeloid Neoplasms: From the Clinical Observation to the Underlying Biology.Semantic proximity Read ↗

The prognostic impact of FLT3-ITD and NPM1 mutation in adult AML is age-dependent in the population-based setting.Semantic proximity Read ↗

A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.Semantic proximity Read ↗

Stratified computational meta-analysis of 2213 acute myeloid leukemia patients reveals age- and sex-dependent gene expression signaturesSemantic proximity Read ↗

Sex Differences in the Spectrum of Clonal HematopoiesisSemantic proximity Read ↗

Beyond XX and XY, Understanding Sex Differences in LeukemiaSemantic proximity Read ↗

Distinct karyotypic and mutational landscape in trisomy AML.Semantic proximity Read ↗

The impact of age, NPM1mut, and FLT3ITD allelic ratio in patients with acute myeloid leukemiaSemantic proximity Read ↗

Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.