Article

p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis

2024-05-21

Abstract excerpt

<h4>ABSTRACT</h4> TP53 is a potent tumour suppressor that coordinates diverse stress response programmes within the cell. The activity of p53 is frequently context and cell type-dependent, and ranges from pro-survival activities, including the implementation of transient cell cycle arrest and metabolic rewiring, through to cell death. In addition to tumour suppressor functions, p53 also has established roles in t...

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Literature Corpus work: e16601bd-cd35-55c1-99b5-fb5aa90fe867
DOI: 10.1101/2024.05.20.594983

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