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Phages rarely encode antibiotic resistance genes: a cautionary tale for virome analyses

21 Jun 2016

Abstract excerpt

Antibiotic resistance genes (ARGs) are pervasive in gut microbiota, but it remains unclear how often ARGs are transferred, particularly to pathogens. Traditionally, ARG spread is attributed to horizontal transfer mediated either by DNA transformation, bacterial conjugation or generalized transduction. However, recent viral metagenome (virome) analyses suggest that ARGs are frequently carried by phages, which is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27326545
DOI: 10.1038/ismej.2016.90

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