Article

Human-specific expansion of 22q11.2 low copy repeats

2020-11-04

Abstract excerpt

Segmental duplications or low copy repeats (LCRs) constitute complex regions interspersed in the human genome. They have contributed significantly to human evolution by stimulating neo- or sub-functionalization of duplicated transcripts. The 22q11.2 region carries eight LCRs (LCR22s). One of these LCR22s was recently reported to be hypervariable in the human population. It remains unknown whether this variability...

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Literature Corpus work: 3ca749ac-f1d6-5f8a-a525-7187be8e0c2a
DOI: 10.1101/2020.11.04.367920

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