Article

Role of trafficking protein particle complex 2 in medaka development

2023-07-14

Abstract excerpt

The skeletal dysplasia spondyloepiphyseal dysplasia tarda (SEDT) is caused by mutations in the TRAPPC2 gene, which encodes Sedlin, a component of the trafficking protein particle (TRAPP) complex that we have shown previously to be required for the export of type II collagen (Col2) from the endoplasmic reticulum. No vertebrate model for SEDT has been generated thus far. To address this gap, we generated a Sedlin k...

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Literature Corpus work: e0cdef3a-5c07-5569-a799-c9a69acc6bdd
DOI: 10.1101/2023.07.14.548998

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