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Article

Crystal structure of SEDL and its implications for a genetic disease spondyloepiphyseal dysplasia tarda.

The Journal of biological chemistry - 20 Dec 2002

Jang Se Bok, Kim Yeon-Gil, Cho Yong-Soon, Suh Pann-Ghill, Kim Kyung-Hwa, Oh Byung-Ha

Abstract excerpt

SEDL is an evolutionarily highly conserved protein in eukaryotic organisms. Deletions or point mutations in the SEDL gene are responsible for the genetic disease spondyloepiphyseal dysplasia tarda (SEDT), an X-linked skeletal disorder. SEDL has been identified as a component of the transport protein particle (TRAPP), critically involved in endoplasmic reticulum-to-Golgi vesicle transport. Herein, we report the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12361953
DOI: 10.1074/jbc.M207436200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Crystal structure of SEDL and its implications for a genetic disease spondyloepiphyseal dysplasia tarda.PMID 12361953Read ↗

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