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Article

The Sec domain protein Scfd1 facilitates trafficking of ECM components during chondrogenesis.

Developmental biology - 1 Jan 2017

Hou Ningning, Yang Yuxi, Scott Ian C, Lou Xin

Abstract excerpt

Chondrogenesis in the developing skeleton requires transformation of chondrocytes from a simple mesenchymal condensation to cells with a highly enriched extracellular matrix (ECM). This transition is in part accomplished by alterations in the chondrocyte protein transport machinery to cope with both the increased amount and large size of ECM components. In a zebrafish mutagenesis screen to identify genes...

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Source

Identifiers

PMID: 27851892
DOI: 10.1016/j.ydbio.2016.11.010

Genes

SCFD1
STX18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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