Article

Regulation of NF-kappa B and cell death by bacterial gingipains

2020-02-26

Abstract excerpt

The role of non-caspase proteases in the regulation of programmed cell death is relatively under-studied. In this short communication, we report that infection of human gingival fibroblast (HGF) cells ex vivo by Porphyromonas gingivalis rapidly activated NF-kappa B, an antiapoptotic player; PI3 kinase was also induced, and together, they inhibited apoptosis. Later, pro-apoptotic cellular genes, including caspase...

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Literature Corpus work: e0850d98-a5bc-525d-a04f-a543666eabfa
DOI: 10.1101/2020.02.25.964585

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