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Article

Intrinsic apoptotic pathways of gingival epithelial cells modulated by Porphyromonas gingivalis.

Cellular microbiology - 1 Aug 2007

Mao Song, Park Yoonsuk, Hasegawa Yoshiaki, Tribble Gena D, James Chlöe E, Handfield Martin, Stavropoulos M Franci, Yilmaz Ozlem, Lamont Richard J

Abstract excerpt

Porphyromonas gingivalis can inhibit chemically induced apoptosis in primary cultures of gingival epithelial cells through blocking activation of the effector caspase-3. The anti-apoptotic phenotype of P. gingivalis is conserved across strains and does not depend on the presence of fimbriae, as fimbriae-deficient mutants and a naturally occurring non-fimbriated strain were able to impede apoptosis. To dissect the...

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Identifiers

PMID: 17419719
DOI: 10.1111/j.1462-5822.2007.00931.x
PMCID: PMC2886729

Genes

JAK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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