Article
Massive dissemination of a SARS-CoV-2 Spike Y839 variant in Portugal.
Emerging microbes & infections - 1 Dec 2020
Borges Vítor, Isidro Joana, Cortes-Martins Helena, Duarte Sílvia, Vieira Luís, Leite Ricardo, Gordo Isabel, Caetano Constantino P, Nunes Baltazar, Sá Regina, Oliveira Ana, Guiomar Raquel, Gomes João Paulo
Abstract excerpt
Genomic surveillance of SARS-CoV-2 was rapidly implemented in Portugal by the National Institute of Health in collaboration with a nationwide consortium of >50 hospitals/laboratories. Here, we track the geotemporal spread of a SARS-CoV-2 variant with a mutation (D839Y) in a potential host-interacting region involving the Spike fusion peptide, which is a target motif of anti-viral drugs that plays a key role in...
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