Article

Single-Cell ATAC-seq analysis via Network Refinement with peaks location information

2022-11-22

Abstract excerpt

Single-cell ATAC-seq (scATAC-seq) data provided new insights into the elaboration of cellular heterogeneity and transcriptional regulation. However, scATAC-seq data posed challenges for data analysis because of its near binarization, high sparsity, and ultra-high dimensionality properties. Here we proposed a novel network diffusion-based method to comprehensively analyze scATAC-seq data, named S ingle- C ell A...

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Literature Corpus work: e072462f-fef2-5760-a7a9-6f302274ce18
DOI: 10.1101/2022.11.18.517159

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