Article

BLM helicase overexpressed in human gliomas contributes to diverse responses of human glioma cells to chemotherapy

2023-03-07

Abstract excerpt

<title>Abstract</title> <p>Most of anti-tumour therapies eliminate neoplastic cells by introducing DNA damage which ultimately triggers cell death. These effects are counteracted by activated DNA repair pathways to sustain tumour proliferation capacity. RECQL helicases family, including BLM, participate in DNA damage and repair, and prevent the replication stress. Glioblastoma (GBM) is a common, malignant brain t...

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Literature Corpus work: e067b031-ef67-5af8-9e92-4449f7431522
DOI: 10.21203/rs.3.rs-2621118/v1

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