Article
Rare bleeding disorders.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2008
Peyvandi F, Cattaneo M, Inbal A, De Moerloose P, Spreafico M
Abstract excerpt
During the haemostatic response, the formation of a primary platelet plug limits bleeding and provides a surface for clotting factors to assemble and become activated. The initial platelet plug is stabilized by fibrin monomers, covalently cross-linked by FXIII, forming a platelets-fibrin thrombus. Defects in platelets as well as inherited deficiencies of coagulation factors including fibrinogen, FII, FV, FV +...
Topics
- Blood Coagulation Disorders, Inherited
- Blood Coagulation Factor Inhibitors
- Blood Platelet Disorders
- Databases, Genetic
- Drug Administration Schedule
- Genotype
- Hemorrhagic Disorders
- Humans
- Medical Records Systems, Computerized
- Phenotype