Article

Targeted knock-in of human immune-regulatory genes into the porcine GGTA1 exon 4 reveals divergent expression on red blood cell membranes

2025-07-16

Abstract excerpt

<title>Abstract</title> <p> The decline in blood donations has become a global challenge, emphasizing the urgent need for alternatives to meet the growing demand. One potential solution is the development of transgenic pigs whose blood can overcome immune rejection and can therefore be used in xenotransfusion. We generated two types of transgenic pigs, one expressing human CD46 ( <italic>hCD46</italic> ) and h...

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Literature Corpus work: e04fa9f8-4672-55f2-871d-f5b9b65751c3
DOI: 10.21203/rs.3.rs-6906665/v1

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Targeted knock-in of human immune-regulatory genes into the porcine GGTA1 exon 4 reveals divergent expression on red blood cell membranesDOI 10.21203/rs.3.rs-6906665/v1Read

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