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Article

Oxidant Stress and Signal Transduction in the Nervous System with the PI 3-K, Akt, and mTOR Cascade

26 Oct 2012

Abstract excerpt

Oxidative stress impacts multiple systems of the body and can lead to some of the most devastating consequences in the nervous system especially during aging. Both acute and chronic neurodegenerative disorders such as diabetes mellitus, cerebral ischemia, trauma, Alzheimer's disease, Parkinson's disease, Huntington's disease, and tuberous sclerosis through programmed cell death pathways of apoptosis and autophagy...

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Share to Autophagy in Disease and Therapy
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PMID: 23203037
DOI: 10.3390/ijms131113830

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