Article

Whole-genome analysis of <i>de novo</i> and polymorphic retrotransposon insertions in Autism Spectrum Disorder

2021-01-31

Abstract excerpt

Retrotransposons are dynamic forces in evolutionary genomics and have been implicated as causes of Mendelian disease and hereditary cancer, but their role in Autism Spectrum Disorder (ASD) has never been systematically defined. Here, we report 86,154 polymorphic retrotransposon insertions including >60% not previously reported and 158 de novo retrotransposition events identified in whole genome sequencing (WGS) d...

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Literature Corpus work: dfe9fc6e-c095-5f81-a98f-4b59a60daedb
DOI: 10.1101/2021.01.29.428895

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