Article

Genome-wide patterns of <i>de novo</i> tandem repeat mutations and their contribution to autism spectrum disorders

2020-03-05

Abstract excerpt

Autism Spectrum Disorder (ASD) is an early onset developmental disorder characterized by deficits in communication and social interaction and restrictive or repetitive behaviors 1,2 . Family studies demonstrate that ASD has a significant genetic basis 3 with contributions both from inherited and de novo variants. While the majority of variance in liability to ASD is estimated to arise from common genetic variat...

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Literature Corpus work: 98597d0c-ee72-5fa2-9a11-dca9474e59ff
DOI: 10.1101/2020.03.04.974170

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