Article

“A Novel Therapeutic Approach to Corneal Alkaline Burn Model by Targeting Fidgetin-like 2, a Microtubule Regulator”

2020-06-19

Abstract excerpt

<h4>Purpose</h4> To determine the efficacy of nanoparticle-encapsulated FL2 siRNA (FL2-NPsi), a novel therapeutic agent targeting the Fidgetin-like 2 (FL2) gene, for the treatment of corneal alkaline chemical injury. <h4>Methods</h4> Eighty 12-week-old, male Sprague-Dawley rats were divided evenly into 8 treatment groups: prednisolone, empty nanoparticles, control-NPsi (1 μM, 10 μM, 20 μM) and FL2-NPsi (1 μM, 10...

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Literature Corpus work: dfe8e9db-f4f4-5aa3-8b72-de06bb8a527b
DOI: 10.1101/2020.06.18.159533

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