Article
Pharmacogenomics in kidney transplant recipients and potential for integration into practice.
Journal of clinical pharmacy and therapeutics - 1 Dec 2020
Nguyen Tam T, Pearson Rachael A, Mohamed Moataz E, Schladt David P, Berglund Danielle, Rivers Zachary, Skaar Debra J, Wu Baolin, Guan Weihua, van Setten Jessica, Keating Brendan J, Dorr Casey, Remmel Rory P, Matas Arthur J, Mannon Roslyn B, Israni Ajay K, Oetting William S, Jacobson Pamala A
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: Pharmacogenomic biomarkers are now used in many clinical care settings and represent one of the successes of precision medicine. Genetic variants are associated with pharmacokinetic and pharmacodynamic changes leading to medication adverse effects and changes in clinical response. Actionable pharmacogenomic variants are common in transplant recipients and have implications for...
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