Article

Genome-wide analysis implicates inner ear development in Ménière’s disease

2026-02-11

Abstract excerpt

Ménière’s disease (MD) is a chronic inner ear disorder characterized by recurrent vertigo, fluctuating sensorineural hearing loss, and tinnitus. Despite these distinctive symptoms, its etiology remains poorly understood. We performed a genome-wide meta-analysis of 8,969 cases and 1,962,542 controls across five large biobanks, identifying five independent genome-wide significant loci and estimating an observed-scal...

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Literature Corpus work: dfbf31a1-350e-533c-8f1b-91eb3df8d5fc
DOI: 10.64898/2026.02.09.26345758

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