Article

In-depth genetic analysis of 6p21.3 reveals insights into associations between HLA types and complex traits and disease

2019-02-28

Abstract excerpt

The highly polymorphic major histocompatibility (MHC) region encodes the human leucocyte antigen (HLA) gene complex and is associated with many autoimmune and infectious diseases. Despite the importance of this interval, comprehensive genetic studies interrogating associations between HLA types, expression of non-HLA genes and disease, have not yet been conducted. To address this issue, we collected high-coverage...

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Literature Corpus work: df77718e-1bd6-5b5e-bbfa-fb69025aba73
DOI: 10.1101/564161

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