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Spatiotemporal Variations in Growth Rate and Virulence Plasmid Copy Number during <i>Yersinia pseudotuberculosis</i> Infection

2020-11-06

Abstract excerpt

Pathogenic Yersinia spp. depend on the activity of a potent virulence plasmid-encoded ysc / yop type 3 secretion system (T3SS) to colonize hosts and cause disease. It was recently shown that Y. pseudotuberculosis up-regulates the virulence plasmid copy number (PCN) during infection and the resulting elevated gene dose of plasmid-encoded T3SS genes is essential for virulence. When and how this novel regulatory...

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Literature Corpus work
df612242-9ea4-5f19-bf92-bdeb93e69a5a
DOI
10.1101/2020.11.04.369199
Open publication

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Spatiotemporal Variations in Growth Rate and Virulence Plasmid Copy Number during <i>Yersinia pseudotuberculosis</i> InfectionDOI 10.1101/2020.11.04.369199
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