Article

Pathogen clonal expansion underlies multiorgan dissemination and organ-specific outcomes during systemic infection

2021-05-17

Abstract excerpt

The dissemination of pathogens through blood and their establishment within organs lead to severe clinical outcomes. However, the within-host dynamics that underly pathogen spread to and clearance from systemic organs remain largely uncharacterized. Here, we investigate the population dynamics of extraintestinal pathogenic E. coli , a common cause of bacteremia, during systemic infection. We show that while bacte...

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Literature Corpus work: 2c7d987e-a31a-5b03-8027-52ba4b7695e7
DOI: 10.1101/2021.05.17.444473

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