Article

Redefining catecholaminergic polymorphic ventricular tachycardia (CPVT) as a neurocardiac condition

2025-01-28

Abstract excerpt

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterised by adrenergic activity-induced sudden cardiac death. It is most often caused by mutations in the RYR2 gene encoding ryanodine receptor 2 (RyR2), which is essential for intracellular calcium handling. Research has traditionally focused on the consequences of mutations at the cardiomyocyte level. However,...

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Literature Corpus work: df48da0e-3ef1-5f55-9979-1b8b82fc46a9
DOI: 10.1101/2025.01.27.635037

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