Article

Molecular mechanisms of aberrant neutrophil differentiation in glycogen storage disease type Ib

2022-01-27

Abstract excerpt

<title>Abstract</title> <p>Glycogen storage disease type Ib (GSD-Ib), characterized by impaired glucose homeostasis, neutropenia, and neutrophil dysfunction, is caused by a deficiency in glucose-6-phosphate transporter (G6PT). Neutropenia in GSD-Ib has been known to result from enhanced apoptosis of neutrophils. However, it has also been raised that neutrophil maturation arrest in the bone marrow would contribute...

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Literature Corpus work: df4044f0-9633-59b9-bea4-aaeb5389c5a7
DOI: 10.21203/rs.3.rs-1271259/v1

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