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Article

Impaired glucose homeostasis, neutrophil trafficking and function in mice lacking the glucose-6-phosphate transporter.

Human molecular genetics - 1 Oct 2003

Chen Li-Yuan, Shieh Jeng-Jer, Lin Baochuan, Pan Chi-Jiunn, Gao Ji-Liang, Murphy Philip M, Roe Thomas F, Moses Shimon, Ward Jerrold M, Lee Eric J, Westphal Heiner, Mansfield Brian C, Chou Janice Yang

Abstract excerpt

Glycogen storage disease type Ib (GSD-Ib) is caused by a deficiency in the glucose-6-phosphate transporter (G6PT). In addition to disrupted glucose homeostasis, GSD-Ib patients have unexplained and unexpected defects in neutrophil respiratory burst, chemotaxis and calcium flux, in response to the...

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PMID: 12925567
DOI: 10.1093/hmg/ddg263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12925567-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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