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Forward and reverse genomic screens enhance the understanding of phenotypic variation in a large Chinese rhesus macaque cohort

2024-08-21

Abstract excerpt

<title>Abstract</title> <p>Combining genotype and phenotype data promises to greatly increase the value of macaque as biomedical models for human disease. Here we launch the Macaque Biobank project by deeply sequencing 919 captive Chinese rhesus macaques (CRM) while assessing 52 phenotypic traits. Genomic analyses revealed CRMs exhibit 1.7-fold higher nucleotide diversity and significantly lower mutational load t...

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Literature Corpus work: df1c341d-ab86-58d3-855b-ca7a3e3fcff8
DOI: 10.21203/rs.3.rs-4800799/v1

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