Article
Genome sequence and global sequence variation map with 5.5 million SNPs in Chinese rhesus macaque.
Genome biology - 6 Jul 2011
Fang Xiaodong, Zhang Yanfeng, Zhang Rui, Yang Lixin, Li Ming, Ye Kaixiong, Guo Xiaosen, Wang Jun, Su Bing
Abstract excerpt
BACKGROUND: Rhesus macaque (Macaca mulatta) is the most widely used nonhuman primate animal in biomedical research. A global map of genetic variations in rhesus macaque is valuable for both evolutionary and functional studies. RESULTS: Using next-generation sequencing technology, we sequenced a Chinese rhesus macaque genome with 11.56-fold coverage. In total, 96% of the reference Indian macaque genome was covered...
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