Article

ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing

2024-08-19

Abstract excerpt

Cranial neural crest (CNC) cells are key stem cells that contribute to most of the facial structures in vertebrates. ADAM ( A D isintegrin A nd M etalloprotease) proteins are essential for the induction and migration of the CNC. We have shown that Adam13 associates with the transcription factor Arid3a to regulate gene expression. Here we show that Adam13 modulates Histone modifications in the CNC. We show that...

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Literature Corpus work: def519d6-3f54-53e1-8352-e028eec1f785
DOI: 10.1101/2024.08.18.608474

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