Article
Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration.
Current biology : CB - 26 Jun 2001
Alfandari D, Cousin H, Gaultier A, Smith K, White J M, Darribère T, DeSimone D W
Abstract excerpt
BACKGROUND: Cranial neural-crest (CNC) cells originate from the lateral edge of the anterior neuroepithelium and migrate to form parts of the peripheral nervous system, muscles, cartilage, and bones of the face. Neural crest-cell migration involves the loss of adhesion from the surrounding neuroepithelium and a corresponding increase in cell adhesion to the extracellular matrix (ECM) present in migratory...
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